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Papers
2 resultsShowing papers from Istituto Ortopedico Rizzoli
ClearSterile inflammation induced by respirable micro and nano polystyrene particles in the pathogenesis of pulmonary diseases
Researchers exposed human lung and immune cells to polystyrene micro and nanoparticles and found they triggered a type of inflammation that does not require infection, called sterile inflammation. Aged (oxidized) particles and those that interacted with immune cells were especially potent at activating inflammatory pathways including the NLRP3 inflammasome. This suggests that breathing in airborne microplastics could cause chronic lung inflammation over time.
Targeting the Inflammatory Hallmarks of Obesity-Associated Osteoarthritis: Towards Nutraceutical-Oriented Preventive and Complementary Therapeutic Strategies Based on n-3 Polyunsaturated Fatty Acids
This review explored nutraceutical-oriented strategies targeting inflammatory pathways in obesity-associated osteoarthritis, examining how bioactive compounds may offer preventive and adjunctive therapeutic approaches for this increasingly prevalent condition.