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Papers
7 resultsShowing papers from Jiangsu Province Hospital
ClearExposure to polyethylene terephthalate micro(nano)plastics exacerbates inflammation and fibrosis after myocardial infarction by reprogramming the gut and lung microbiota and metabolome
Researchers found that PET microplastics and nanoplastics, one of the most common plastic types found in human coronary blood, worsen heart damage after a heart attack. The plastic particles activated an inflammatory pathway (NLRP3) and disrupted the balance of gut and lung bacteria, leading to chronic inflammation and increased scarring of heart tissue. These findings suggest that plastic pollution exposure may make recovery from heart attacks more difficult.
Exposure to irregular microplastic shed from baby bottles activates the ROS/NLRP3/Caspase-1 signaling pathway, causing intestinal inflammation
Researchers found that baby bottles made of polypropylene release irregularly shaped microplastics when exposed to boiling water or microwave heating, and these particles triggered inflammation in human intestinal cells. The microplastics activated a specific inflammatory pathway (NLRP3 inflammasome) that caused oxidative stress and elevated levels of pro-inflammatory signals. This is especially concerning for infant health, as babies may be exposed to these particles daily through heated formula and milk.
Multi-Omics Analysis Reveals the Toxicity of Polyvinyl Chloride Microplastics toward BEAS-2B Cells
Researchers used advanced gene and metabolite analysis to reveal how PVC microplastics damage human lung cells. Exposure altered the expression of 530 genes and nearly 4,000 metabolites, particularly disrupting fat metabolism pathways and activating inflammatory stress responses. These findings are important because airborne PVC microplastics are common in indoor and outdoor environments, and the study reveals specific biological pathways through which inhaled microplastics could contribute to lung disease.
The landscape of micron-scale particles including microplastics in human enclosed body fluids
Researchers conducted the first comprehensive survey of micron-scale particles, including microplastics, across thirteen types of human body fluids spanning eight organ systems. They detected microparticles in multiple enclosed body fluids, with polyethylene and polyamide among the most common plastic types found. The findings suggest that microplastic exposure in humans is more widespread than previously understood, with particles reaching diverse internal compartments.
Melatonin attenuates polystyrene microplastics induced motor neurodevelopmental defect in zebrafish (Danio rerio) by activating nrf2 - isl2a Axis
Researchers found that melatonin protected zebrafish embryos from polystyrene microplastic-induced motor neuron developmental defects by activating the Nrf2-Isl2a signaling pathway, reducing oxidative stress and restoring normal motor neuron axon development.
A Bibliometric Analysis of Research Trends of Acupuncture Therapy in the Treatment of Migraine from 2000 to 2020
This bibliometric analysis reviewed research trends in acupuncture therapy for migraine treatment from 2000 to 2020, identifying major publication patterns and emerging research directions. It has no relevance to microplastic or environmental health research.
Analysis of microplastics released from plastic take-out food containers based on thermal properties and morphology study
This study measured microplastics released from three types of plastic take-out food containers — polypropylene, polyethylene, and expanded polystyrene — when filled with hot water. Expanded polystyrene released the most particles by far (up to 2.8 million per liter), and over 96% of particles from all containers were smaller than 10 micrometers, small enough to be absorbed into the gut.