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Papers
3 resultsShowing papers from Second Affiliated Hospital of Xi'an Jiaotong University
ClearCarboxyl-modified polystyrene microplastics induces neurotoxicity by affecting dopamine, glutamate, serotonin, and GABA neurotransmission in Caenorhabditis elegans
Researchers used the nematode C. elegans as a model to study how carboxyl-modified polystyrene microplastics affect the nervous system. They found that even at low concentrations, these modified microplastics caused more severe neurotoxicity than unmodified polystyrene, disrupting dopamine, glutamate, serotonin, and GABA neurotransmission. The study suggests that surface modifications on microplastics may significantly increase their potential to cause neurological harm.
Multidisciplinary recommendations for the management of CAR-T recipients in the post-COVID-19 pandemic era
This review provides multidisciplinary guidelines for managing patients who received CAR-T cell therapy during and after the COVID-19 pandemic. Researchers note that these patients face heightened infection risks due to their suppressed immune systems and require careful monitoring and vaccination strategies. The study offers practical recommendations for clinicians balancing cancer treatment decisions with ongoing infectious disease threats.
Micro- and nanoplastic (MNPs) exposure at single-cell resolution impaired placental function and cellular dynamics
Researchers performed single-cell transcriptomic analysis of placentas from pregnant women exposed to micro- and nanoplastics, finding that MNP exposure altered trophoblast, macrophage, and fibroblast subpopulations, suggesting impaired placental function through disruption of cell communication and immune regulation.