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Papers
2 resultsShowing papers from Kyung Hee University Medical Center
ClearInhalation of dust accumulated on personal computer fans in the office may cause pathological effects by disrupting the metabolic activity of alveolar macrophages
Researchers collected dust from personal computer fans in offices and found it contained various types of microplastics and non-protein particles. When mice were exposed to this dust over 90 days, they developed lung inflammation, foamy macrophages, mitochondrial damage, and collagen fiber formation in lung and heart tissues. The study suggests that inhaling office dust containing microplastics may disrupt metabolic activity in lung cells and contribute to respiratory and cardiovascular effects.
Inhaled polystyrene nanoparticles may cause fibrotic lesions via immune dysregulation and energy metabolism disturbance
Mice received polystyrene nanoparticles via pharyngeal instillation for 90 days and were assessed for local lung and systemic toxicity. The nanoparticles accumulated in lungs and hearts, caused immune dysregulation, disrupted energy metabolism, and induced fibrotic lesions at higher doses, suggesting that chronic inhalation of nanoplastics may contribute to pulmonary fibrosis.