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Article Tier 2

Mutational signatures associated with exposure to carcinogenic microplastic compounds bisphenol A and styrene oxide

Researchers exposed human cells to bisphenol A and styrene oxide and identified genome-wide mutational signatures dominated by guanine-targeted substitutions, finding similar mutation patterns in tumor samples from digestive and urinary organ cancers, supporting carcinogenic potential.

2021 NAR Cancer 42 citations