Papers

2 results

All Human Health Effects 25,424 Gut & Microbiome 6,526 Reproductive & Development 3,270 Food & Water 8,916 Nanoplastics 9,972 Detection Methods 17,548 Remediation 21,169 Marine & Wildlife 30,770 Environmental Sources 38,037 Policy & Risk 19,660

Article Tier 2

The joint effects of nanoplastics and TBBPA on neurodevelopmental toxicity in<i>Caenorhabditis elegans</i>

Researchers used the model organism C. elegans to study the combined neurodevelopmental effects of polystyrene nanoplastics and the flame retardant TBBPA. The study found that combined exposure produced synergistic harmful effects including reduced survival, impaired movement, oxidative stress, and dopaminergic neuron loss, with specific genes related to neurodegenerative pathways playing key roles in the observed toxicity.

2023 Toxicology Research 20 citations

Article Tier 2

Neurodevelopmental Toxicity of Polystyrene Nanoplastics in<i>Caenorhabditis elegans</i>and the Regulating Effect of Presenilin

C. elegans exposed to 25, 50, and 100 nm polystyrene nanoplastics showed size-dependent neurodevelopmental toxicity — including reactive oxygen species generation, mitochondrial damage, and inhibited dopamine production — with smaller particles (25 nm) paradoxically showing weaker effects than the 50 nm size.

2020 ACS Omega 64 citations