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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Nanoplastics Sign in to save

Exposure to polystyrene nanoparticles leads to dysfunction in DNA repair mechanisms in Caco-2 cells

Biological Research 2025 6 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Agata Kustra, Mirosław Zając, Piotr Bednarczyk, Kamila Maliszewska‐Olejniczak

Summary

Researchers found that exposing intestinal cells (Caco-2) to polystyrene nanoplastics impaired DNA repair mechanisms even at doses that didn't kill the cells, raising concern that nanoplastic exposure could lead to genetic instability and long-term health risks over time.

Polymers

This study highlights the sublethal effects of nanoplastics on intestinal barrier cells. It underscores the possible risks of exposure to these environmental contaminants, which can lead to genome instability and other long-term health consequences.

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