We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Study on Chemically-induced Diet Alteration of Drosophila Melanogaster
Summary
This study used Drosophila melanogaster as an in vivo model to assess how chemical compounds — including plastic-associated chemicals — alter feeding behavior and development, evaluating the fruit fly's diet alteration response as a sensitive toxicity endpoint for environmental contaminant screening.
Toxicity assesment of chemical compounds that can end up into the environment is extremely important as chemicals have the ability to enter in biological organisms via different pathways and therefore reshape organisms' development.In vitro tests are successfully used to test chemical compounds, but do not provide an overall insight into the toxic potential they may have once reach a whole organism.Study models validated by repeated research, such as Drosophila melanogaster, are used to perform in vivo tests.One of the most significant parameters for testing the toxicity of compounds on the fruit fly is viability.An effective method to study viability in relation to various exogenous substances is by altering the diet of the test organisms.The main aim of the study is to better understand the impact that some chemicals have on animal organisms and to observe the response of fruit fly to different classes of compounds as seen from the viability perspective.Thus, in order to investigate the effects of chemicals we have altered the culture media by adding either natural compounds (different types of water, phytoestrogens) or synthetic compounds (nanoparticles, pesticides).Our findings suggest that the different types of water do not affect the viability of fuit flies and this has also been proven for nanoparticles.Regarding pesticides and phytoestrogens, there is a decrease in viability percentages in a dose-dependent manner.
Sign in to start a discussion.
More Papers Like This
Intake of polyamide microplastics affects the behavior and metabolism of Drosophila
Researchers found that exposure to polyamide microplastics altered feeding behaviour, reduced triglyceride and protein levels, and disrupted metabolism in Drosophila, with effects differing between sexes and increasing in severity at higher microplastic concentrations.
Toxicological Profile of Polyethylene Terephthalate (PET) Microplastic in Ingested Drosophila melanogaster (Oregon R+) and Its Adverse Effect on Behavior and Development
Researchers fed PET microplastics to fruit flies and found that the particles accumulated in their bodies and caused dose-dependent declines in movement, climbing ability, and survival rates. Higher microplastic concentrations also slowed the flies' development from larvae to adults. While fruit flies are a simple model organism, these behavioral and developmental effects suggest that chronic microplastic ingestion could impair neurological and physiological functions in animals exposed through their diet.
The effects of microplastics and nanoplastics upon history, policies, and Drosophila melanogaster
This study examined the effects of microplastics and nanoplastics on the fruit fly Drosophila melanogaster, finding that dietary exposure to these pervasive environmental contaminants causes measurable biological harm and making the case for stronger regulatory policies.
Transgenerational effects on development following microplastic exposure in Drosophila melanogaster
Researchers fed Drosophila melanogaster flies plastic-supplemented food and found that while treated flies showed changes in fertility and sex ratio, their unexposed offspring had shorter larval development and reduced adult size, demonstrating transgenerational developmental effects from parental microplastic exposure.
Effects of PET microplastics on the physiology of Drosophila
Researchers used Drosophila fruit flies as a model to study the physiological effects of PET microplastics, finding that ingestion affected reproduction, lifespan, and gut function. The study suggests that even common plastic types found in food packaging can have measurable biological effects when consumed by living organisms.