We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Effects of chronic co-exposure polystyrene nanoplastics and cadmium on liver function in Prussian carp (Carassius gibelio)
AI summary Read the abstract
Researchers exposed Prussian carp to polystyrene nanoplastics and cadmium, both individually and together, for 21 days and found that the combination caused significantly worse liver damage than either pollutant alone. The nanoplastics enhanced cadmium accumulation in the liver and amplified oxidative stress, tissue damage, and immune gene activation. The findings demonstrate that nanoplastics and heavy metals can have synergistic toxic effects on aquatic organisms.
Nanoplastics (NPs) are tiny plastic particles that arise from the degradation of microplastics. They have an extensive presence in aquatic environments and exert high ecotoxicity in aquatic organisms. In this study, Prussian carp (Carassius gibelio) was used to assess the hepatotoxicity of polystyrene nanoplastics (PS-NPs) and cadmium (Cd) following 21 days of individual and combined exposures. The results showed that co-exposure to PS-NPs and Cd enhanced PS-NPs accumulation in the liver. Compared to their individual effects, simultaneous exposure to PS-NPs and Cd led to more severe histopathological damage to liver tissue and increased liver transaminases activities. Additionally, this co-exposure resulted in decreased superoxide dismutase (SOD) activity, with increased malondialdehyde (MDA) and total antioxidant capacity (T-AOC). Moreover, the transcriptional levels of immune-associated genes were up-regulated. In conclusion, PS-NPs and Cd exhibit synergistic toxic effects on the liver of Prussian carp. These findings offer crucial insights into the combined hepatotoxicity of NPs and heavy metals in aquatic organisms, suggesting potential risks to human health.
More Papers Like This
Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio)
AI summary Read the abstract
Researchers investigated the individual and combined toxicity of cadmium and polystyrene microplastics on common carp over 30 days. They found that co-exposure to both pollutants produced more severe effects on liver enzymes, immune function, and biochemical markers than either pollutant alone. The study suggests that microplastics can enhance the toxicity of heavy metals in aquatic organisms, raising concerns about the combined impact of these co-occurring contaminants.
Effects of polystyrene nanoplastics on Ctenopharyngodon idella (grass carp) after individual and combined exposure with zinc oxide nanoparticles
AI summary Read the abstract
Researchers studied the individual and combined toxic effects of polystyrene nanoplastics and zinc oxide nanoparticles on grass carp. They found that co-exposure caused more severe oxidative stress, immune suppression, and gill tissue damage than either pollutant alone. The study suggests that interactions between nanoplastics and metal nanoparticles in aquatic environments can produce synergistic toxic effects on freshwater fish.
Combined impacts of microplastics and cadmium on the liver function, immune response, and intestinal microbiota of crucian carp (Carassius carassius)
AI summary Read the abstract
Researchers exposed crucian carp to microplastics and cadmium, both alone and together, and found the combination caused more severe liver damage and immune disruption than either pollutant alone. Co-exposure also significantly altered the fish's gut bacteria after 21 days. This is concerning because microplastics and heavy metals frequently co-occur in polluted waterways, potentially amplifying harm to aquatic life.
Single and combined effects of microplastics and cadmium on juvenile grass carp (Ctenopharyngodon idellus)
AI summary Read the abstract
Researchers found that combined exposure to polystyrene microplastics and cadmium in juvenile grass carp caused greater physiological stress than either pollutant alone, with microplastics enhancing cadmium accumulation and intensifying oxidative stress and immune responses.
Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio)
AI summary Read the abstract
Researchers exposed zebrafish to polystyrene microplastics combined with cadmium for three weeks and found that the presence of microplastics significantly increased cadmium accumulation in the liver, gut, and gills. The combined exposure caused greater oxidative damage, tissue inflammation, and disruption of protective gene activity than either pollutant alone. The study demonstrates that microplastics can enhance the toxicity of heavy metals in fish by acting as carriers that increase the body's uptake of harmful substances.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.