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Transgenerational effects of water-soluble polymers on Daphnia magna at environmentally relevant concentrations: The role of multigenerational plasticity
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Researchers exposed Daphnia magna water fleas to environmentally relevant concentrations (1 µg/L) of water-soluble polymers PEG and PVA across three generations, finding that PEG initially reduced reproduction and increased DNA methylation in the first generation, but subsequent generations showed compensatory recovery. These findings suggest multigenerational epigenetic plasticity and highlight the need for regulatory oversight of water-soluble polymers.
The widespread use of water-soluble polymers (WSPs) like polyethylene glycol (PEG) and polyvinyl alcohol (PVA) across multiple industrial and household uses has recently raised concerns about their environmental persistence and potential toxicity to aquatic organisms. Despite being excluded from regulatory oversight, recent studies suggest possible ecological risks associated with sub-lethal exposures to these polymers. In this context, this study investigates the transgenerational effects of PEG and PVA on Daphnia magna, focusing on both life-history parameters and epigenetic modifications at the environmentally relevant concentration of 1 μg/L. Through continuous exposure experiments, spanning three generations (from F0 to F3), and "recovery" groups, where only the parental generation (F0) was exposed, our results reveal significant reductions in the number of newborns and reproductive parameters in the F0 generation exposed to PEG but not in subsequent generations. This suggests a multigenerational plasticity in Daphnia through a compensatory or acclimation reproductive response over time. Global cytosine methylation patterns also showed a significant initial increase in the F0 generation exposed to PEG, which decreased in later generations, indicating a possible epigenetic mechanism underlying observed reproductive effects. In contrast, PVA exhibited no significant changes in both life history parameters and methylation but showed a global methylation trend suggesting its likely epigenetic influence. These findings underscore the need for comprehensive risk assessments of WSPs, particularly their potential for inducing long-term (epigenetic) effects, influencing reproductive functions across generations and how increased plasticity may affect responses against novel other stressors.
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This study investigated the effects of four common water-soluble polymers, including polyvinyl alcohol and polyethylene glycol, on the freshwater organism Daphnia magna. Researchers found that these widely used industrial chemicals can affect the organisms at multiple biological levels, from protein expression changes to altered swimming behavior, indicating that water-soluble polymers deserve more attention as aquatic pollutants.
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Researchers exposed Daphnia magna to polyethylene microplastics containing benzophenone-3 for a single generation and then tracked effects through three subsequent unexposed generations. The study found persistent epigenetic changes across all four generations, including six genes that remained altered throughout, affecting pathways related to detoxification, development, and cardiovascular function, challenging current assumptions about how environmental risk from microplastics should be assessed.
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Researchers investigated the multi-generational effects of microplastic fiber exposure on the water flea Daphnia magna across three generations. They found that microplastic fibers negatively affected reproduction and survival, and these effects persisted into unexposed generations through epigenetic changes. The study reveals that microplastic pollution may cause lasting harm to aquatic populations through inherited biological alterations, not just direct exposure.
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This study exposed water fleas to polyethylene and polystyrene microplastics and found that both types caused changes in gene activity and epigenetic modifications, which are chemical changes that affect how genes work without altering the DNA itself. Polystyrene caused more severe effects, altering genes involved in stress response, immune function, and reproduction. These epigenetic changes are concerning because they can potentially be passed to future generations, suggesting microplastics could have long-lasting biological effects beyond direct exposure.
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Researchers exposed water fleas (Daphnia magna) to polyethylene and polystyrene microplastics and examined changes at the genetic and molecular level. They found that the microplastics altered DNA methylation patterns and disrupted the expression of genes involved in reproduction and stress response. The study provides evidence that microplastic exposure can cause changes beyond physical harm, affecting organisms at the epigenetic level.
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