Multi-omic Approach on the Ecotoxicological Assessment of Microplastics, Antibiotics and Their Co-exposure to Zebrafish

Summary

This PhD thesis investigated co-exposure effects of microplastics and antibiotics on zebrafish using multi-omic approaches, examining transcriptomic, proteomic, and metabolomic responses. Combined exposure produced more complex molecular disruption than either stressor alone, with interactions affecting gut microbiome composition and host metabolic phenotype.