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Polystyrene nanoplastic exposure promotes amyloid misfolding and metabolic impairment at sublethal doses. A subcellular infrared imaging study
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Sub-diffraction O-PTIR infrared imaging revealed that polystyrene nanoplastics penetrate cells at sublethal doses and promote pathological amyloid-beta protein misfolding associated with neurodegenerative disease. This finding raises serious concern about nanoplastic exposure as a potential contributor to metabolic and neurological impairment at environmentally relevant concentrations.
Sub-diffraction O-PTIR imaging reveals that polystyrene nanoplastics penetrate cells and promote pathological amyloid-β misfolding at sublethal doses.
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