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Heterologous expression and characterization of Rhodococcus opacus R7 laccase-like multicopper oxidase (LMCO1) enzyme for polyethylene biodegradation

The Journal of Physical Chemistry B 2026
Mahboobeh Pishan, Sima Sazegari, A.D. Niazi, Marjan Majdinasab, Zahra Zinati, Mohammad Hadi Eskandari

Summary

Researchers heterologously expressed a laccase-like multicopper oxidase enzyme from Rhodococcus opacus R7 and characterized its capacity for oxidative degradation of polyethylene, exploring a biological route to breaking down one of the most common and persistent plastic polymers.

Polymers

The production rate of Polyethylene (PE) has increased to a concerning level, necessitating effective strategies to reduce its environmental impacts. This study investigates the role of laccase-like multicopper oxidase (LMCO1) in oxidative degradation of PE, through a comprehensive approach, i...

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