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Polystyrene microplastics impair growth, DNA integrity, and metabolic function in Vigna radiata: A multilevel toxicological assessment
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Researchers reviewed the environmental presence, transport pathways, and biological impacts of polystyrene microplastics, documenting how widespread food packaging use leads to pervasive contamination of aquatic and terrestrial ecosystems and raises concerns for organismal and human health.
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Researchers orally exposed male Wistar rats to polystyrene microplastics at three doses over four weeks and found dose-dependent disruption of renal energy metabolism, including impaired glycolysis, suppressed gluconeogenesis, and a metabolic shift toward anaerobic pathways, accompanied by progressive histopathological damage including tubular inflammation and loss of Bowman's capsular space.
The Impact of Polystyrene Microplastics in Living Organisms; Environmental and Ecological Concerns
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This review comprehensively examined the environmental and ecological impacts of polystyrene microplastics, which readily adsorb both organic and inorganic pollutants and carry them into living organisms. Polystyrene is one of the most widely produced plastics globally, and its breakdown into microplastics creates particles that act as vectors for toxic chemicals in ecosystems and potentially in human bodies.
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Comprehensive toxicity testing of polystyrene microplastics on Daphnia magna showed that 1-µm particles were most toxic (48-h LC50: 23.57 mg/L), reducing swimming speed and feeding behavior while triggering oxidative stress markers including elevated malondialdehyde. These behavioral and biochemical endpoints serve as sensitive early-warning biomarkers for ecological risk, highlighting how nanoscale plastics impair the zooplankton that form the base of aquatic food webs.
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