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Multi-omics analysis reveals polyethylene microplastics-induced gill damage, metabolic disruption and immune dysregulation in Lateolabrax maculatus

Chemico-Biological Interactions 2026
Changhong Lin, Mingze Gao, Huilong Chen, Jieyun Guo, Bo Zhang, Jiangtian Lin, Chao Zhao

Summary

Researchers exposed spotted sea bass (Lateolabrax maculatus) to dietary polyethylene microplastics and found that even moderate concentrations caused gill tissue damage, oxidative stress, and immune dysregulation by disrupting energy metabolism and NF-κB inflammatory pathways, with most effects showing partial recovery after a 14-day depuration period.

Polymers
Body Systems

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