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Nanoplastic Impact on Human Health—A 3D Intestinal Model to Study the Interaction with Nanoplastic Particles
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Researchers used a three-dimensional intestinal model to study how nanoplastic particles interact with human gut tissue, finding that nanoplastics can cross the intestinal epithelial barrier and induce inflammatory responses, providing more physiologically relevant evidence than prior two-dimensional cell culture studies of nanoplastic health risks.
Much attention has been paid in recent years to the fate of microplastics in the environment. Several studies have shown that microplastics can be taken up by a variety of organisms (e.g., fish, mussels, zooplankton, sea urchin, birds) and thus can cause adverse...
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Nanoplastic-Induced Biological Effects In Vivo and In Vitro: An Overview
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Researchers reviewed how nanoplastics accumulate in and harm living organisms, finding that particle size, surface charge, exposure dose, and duration all influence toxicity — with smaller, charged particles penetrating cells more readily and chemical additives amplifying harm beyond the plastics themselves.
Microplastics and nanoplastics in the human gut: from signals to standards
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Researchers outlined major methodological gaps in current studies on microplastic and nanoplastic exposure through the human gastrointestinal tract, proposing minimum standards for study design and reporting to move the field from preliminary signals toward causal evidence linking gut plastic exposure to specific health outcomes.
Micro-nano Plastics: Impact on Gastrointestinal System
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Researchers reviewed how micro- and nanoplastics affect the gastrointestinal system, finding that ingested plastic particles can disrupt gut lining integrity, alter the gut microbiome, trigger inflammation, and may contribute to digestive disorders — raising concern given that humans ingest microplastics daily through food, water, and air.
3D Printer Waste Nanoparticles and Their Internalization in Human Colorectal Cells (HCT15), as in Vitro Cell Model of Nanoplastics Absorption
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3D printers can shed tiny plastic particles (nanoplastics) during the printing process, and this study found that when these particles were applied to human colon cells in a lab dish, they caused cell stress and damaged the cells' energy-producing mitochondria, especially at higher doses. This matters because it adds to growing evidence that plastic pollution, already found in human waste and even the placenta, may pose real risks to our cells, and it's a reminder to handle 3D printing waste carefully and push for better recycling as this technology becomes more common in homes and workplaces.
Impact of Micro-nanoplastics on Gut and Immune Function
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This review examined how micro- and nanoplastics disrupt gut microbiota and immune function across aquatic and terrestrial vertebrates, with implications for human health. Because the gut microbiome governs immune regulation and metabolic health, microplastic-induced dysbiosis represents a plausible mechanism by which plastic ingestion could drive systemic inflammation and disease beyond the GI tract.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.