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Screening for bioactivities in three types of microplastics deployed in Swedish aquatic environments using a battery of reporter gene assays
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This study screened three types of microplastics deployed in Swedish aquatic environments for biological activity using reporter gene assays, testing whether leachates from the plastics could activate specific cellular signaling pathways. Identifying bioactive compounds associated with environmental microplastics helps assess their potential toxicity to aquatic organisms.
Screening for bioactivities in three types of microplastics deployed in Swedish aquatic environments using a battery of reporter gene assays
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Phenotypic and Gene Expression Alterations in Aquatic Organisms Exposed to Microplastics
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This review summarizes research on how microplastics affect aquatic animals at the genetic level, covering changes in hatching, development, and growth. Microplastics, especially when combined with other pollutants, trigger abnormal gene activity in antioxidant and stress-response systems in fish and other water organisms. These genetic disruptions in aquatic life are relevant to human health because affected organisms can enter the food chain through seafood.
Toxicity assessment of pollutants sorbed on microplastics using various bioassays on two fish cell lines
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Researchers collected microplastic samples from ocean expeditions and tested their toxicity using two fish cell lines, finding that cell lines differed in sensitivity and that microplastics with sorbed pollutants were toxic to cells. The results suggest that real-world microplastics carrying accumulated chemical pollutants pose a chemical toxicity risk to marine organisms beyond just the physical effects of ingesting plastic.
Genes of filter-feeding species as a potential toolkit for monitoring microplastic impacts
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Researchers developed a genetic toolkit using candidate genes from filter-feeding marine species to monitor the biological impacts of microplastic exposure in natural environments. They identified six genes across nine species that show measurable expression changes when organisms encounter microplastics. The study offers a practical molecular approach for tracking how microplastic pollution is actually affecting wild marine populations.
Toxicity assessment of pollutants sorbed on environmental sample microplastics collected on beaches: Part I-adverse effects on fish cell line
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Environmental microplastics from Pacific island beaches were tested on rainbow trout liver cells (RTLW-1), with MPs from all three island locations causing cytotoxicity and inducing metabolic enzyme activity, while virgin MPs showed no significant effects. The study demonstrates that contaminant loading on beach-collected microplastics drives cell-level toxicity beyond the physical plastic particle effects alone.
Structure activity toxicity of different micro-nanoplastics on developing Zebrafish (Danio rerio) based on individual polymer chemistry
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This dissertation examined the toxicity of individual polymer chemistries—rather than generic microplastic mixtures—on zebrafish embryos and larvae, finding polymer-specific differences in developmental toxicity, behavioral disruption, and biochemical pathway activation across multiple plastic types.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.