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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Detection Methods Gut & Microbiome Human Health Effects Marine & Wildlife Policy & Risk Remediation Sign in to save

Evaluation of existing methods to extract microplastics from bivalve tissue: Adapted KOH digestion protocol improves filtration at single-digit pore size

Marine Pollution Bulletin 2019 264 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Christina J. Thiele, Christina J. Thiele, Christina J. Thiele, Christina J. Thiele, Christina J. Thiele, Christina J. Thiele, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Andrea E. Russell Andrea E. Russell Andrea E. Russell Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Malcolm D. Hudson, Andrea E. Russell Andrea E. Russell Malcolm D. Hudson, Andrea E. Russell Andrea E. Russell

Summary

Researchers compared several existing methods for extracting microplastics from bivalve tissue, including hydrogen peroxide, enzymatic digestion, and potassium hydroxide treatments. They found that only the KOH method allowed filtration through very fine filters down to 1.2 micrometers when a neutralization step was added, enabling recovery of much smaller microplastics. The study recommends KOH digestion as the most practical extraction method for studies aiming to assess human exposure risk from consuming shellfish.

Methods standardisation in microplastics research is needed. Apart from reagent-dependent effects on microplastics, varying target particle sizes can hinder result comparison between studies. Human health concerns warrant recovery of small microplastics. We compared existing techniques using hydrogen peroxide, Proteinase-K, Trypsin and potassium hydroxide to digest bivalve tissue. Filterability, digestion efficacy, recoverability of microplastics and subsequent polymer identification using Raman spectroscopy and a matching software were assessed. Only KOH allowed filtration at ≤25 μm. When adding a neutralisation step prior to filtration, KOH digestates were filterable using 1.2-μm filters. Digestion efficacies were >95.0% for oysters, but lower for clams. KOH destroyed rayon at 60 °C but not at 40 °C. Acrylic fibre identification was affected due to changes in Raman spectra peaks. Despite those effects, we recommend KOH as the most viable extraction method for exposure risk studies, due to microplastics recovery from bivalve tissues of single-digit micrometre size.

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