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Polystyrene microplastic exposure alters the shell matrix proteome and compromises biomineralization in the freshwater snail Planorbarius corneus

Aquatic Toxicology 2025
Chuang Liu, Guoping Chen, Jindong Xu

Summary

Freshwater snails (Planorbarius corneus) were exposed to 5 µm polystyrene microplastics for 51 days, leading to reduced shell growth rates and altered shell matrix proteome composition compared to controls. The disruption of biomineralization-related proteins suggests polystyrene MPs impair a fundamental physiological process in molluscs.

Polymers
Study Type Environmental

The continuous growth of plastic production makes microplastic pollution a globally significant environmental issue. Biomineralization, vital for mollusk growth and development, provides essential shell protection and support. However, studies on microplastic impacts on freshwater snail biomineralization remain scarce. This research exposed Planorbarius corneus snails to 5-μm polystyrene microplastics for 51 days. The control group exhibited significantly higher shell-width growth rates and egg-laying volumes than the exposed group. Proteomic analysis of shell matrix proteins (SMPs) via liquid chromatography-tandem mass spectrometry identified 213 SMPs in controls versus 189 in high-concentration exposed snails. Microplastics altered SMP composition and abundance, affecting tyrosinases, acidic matrix proteins, macroglobulins, and globins. This study reveals fundamental proteome-level disruptions in shell biomineralization caused by microplastics in freshwater snails.

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