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Data from: Polystyrene nanoplastics impact the bioenergetics of developing zebrafish and limit molecular and physiological adaptive responses to acute temperature stress

Research Data Repository, Duke University 2026
Rafael Trevisan, Rafael Trevisan, Lynette Butron, Kimbergly Gaston, Rose Trimpey-Warhatfig, Rich T. Di Giulio, Shaza Gaballah

Summary

This dataset accompanies research on how polystyrene nanoplastics affect developing zebrafish under heat stress conditions. The data include measurements of antioxidant responses, apoptosis levels, growth metrics, heart rate, survival, hatching rates, and mitochondrial function, documenting how nanoplastic exposure can disrupt cellular physiology and limit adaptive responses to temperature stress.

Polymers
Body Systems

Plastic pollution is a growing environmental concern due to its ubiquitous impact on aquatic ecosystems. Nanoplastics can be generated from the breakdown of plastic waste and interact with organisms at the cellular level, potentially disrupting cellular physiology. We investigated the effects of 44 nm polystyrene nanoparticles (44 nm NanoPS) on the development and physiology of zebrafish (Danio rerio) in the presence of sublethal heat stress (32 °C vs control, 28 °C). Data herein includes antioxidant responses, levels of apoptosis, body metrics, feeding rates, heart rate, survival, hatching rates, and mitochondrial bioenergetics.

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