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Microplastics, microfibres and nanoplastics cause variable sub-lethal responses in mussels (Mytilus spp.)

Marine Pollution Bulletin 2020 223 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Matthew Cole, Corin Liddle, Giulia Consolandi, Claudia Drago, Cameron Hird, Penelope K. Lindeque, Tamara S. Galloway

Summary

Researchers compared the toxic effects of microplastics, microfibres, and nanoplastics on mussels over 24-hour and 7-day exposures. They found that nanoplastics triggered a heightened immune response, while all plastic types caused initial oxidative stress that returned to normal levels after a week. The study highlights that particle size is a key factor in determining the type and severity of biological responses to plastic pollution in marine organisms.

We compare the toxicity of microplastics, microfibres and nanoplastics on mussels. Mussels (Mytilus spp.) were exposed to 500 ng mL-1 of 20 μm polystyrene microplastics, 10 × 30 μm polyamide microfibres or 50 nm polystyrene nanoplastics for 24 h or 7 days. Biomarkers of immune response, oxidative stress response, lysosomal destabilisation and genotoxic damage were measured in haemolymph, digestive gland and gills. Microplastics and microfibres were observed in the digestive glands, with significantly higher plastic concentrations after 7-days exposure (ANOVA, P < 0.05). Nanoplastics had a significant effect on hyalinocyte-granulocyte ratios (ANOVA, P < 0.05), indicative of a heightened immune response. SOD activity was significantly increased followed 24 h exposure to plastics (two-way ANOVA, P < 0.05), but returned to normal levels after 7-days exposure. No evidence of lysosomal destabilisation or genotoxic damage was observed from any form of plastic. The study highlights how particle size is a key factor in plastic particulate toxicity.

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