Back to papers
0
Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Environmental Sources Policy & Risk Sign in to save

Palliative effect of taurine against hepatic injury induced by polystyrene microplastics through antioxidant and metabolic pathway modulation in mice

Frontiers in Pharmacology 2025 2 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Areej A. Eskandrani, Amany Abdel-Rahman Mohamed, Badriyah S. Alotaibi, Yasmina M. Abd‐Elhakim, Tarek Khamis, Ahmed E. Noreldin, Ahmed E. Abdelhamid, Nawal Alsubaie, Nawal Alsubaie, Leena S. Alqahtani

Summary

Researchers found that polystyrene microplastics caused liver damage in an animal model through oxidative stress and lipid metabolic disruption, and that taurine supplementation exerted a protective effect by modulating oxidative and metabolic pathways. The results support taurine as a potential therapeutic agent for microplastic-induced hepatotoxicity.

Polymers
PS
Body Systems
Hepatic
Models
Mouse

Overall, the findings indicated that PS-MPs caused liver damage via oxidative stress and lipid metabolic disturbance, and that Tau supplementation had a protective effect, possibly via modulating oxidative and metabolic pathways. This experiment emphasized the necessity for additional research into Tau as a therapeutic agent in microplastic-related liver damage.

Read via DOI PubMed PMC Full Text Download PDF

Share this paper

Post Share Share Pin Email