Back to papers
0
Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Nanoplastics Sign in to save

Fabrication of polyethylene terephthalate (PET) nanoparticles with fluorescent tracers for studies in mammalian cells

Nanoscale Advances 2020 52 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Leah M. Johnson, Jeffrey B. Mecham, Sai Archana Krovi, Maria Moreno Caffaro, Shyam Aravamudhan, Alexander L. Kovach, Timothy R. Fennell, Ninell P. Mortensen

Summary

Fluorescent polyethylene terephthalate (PET) nanoparticles with a hydrodynamic diameter of 158 nm were synthesized in a bottom-up approach for use as research tools. Concentration-dependent uptake and cytotoxicity were demonstrated in macrophages, providing well-characterized PET nanoplastic models for studying cellular interactions.

Polymers
PE PET
Body Systems
Immune

Fluorescent nanoparticles (NPs) comprising polyethylene terephthalate (PET) with a hydrodynamic diameter of 158 ± 2 nm were synthesized in a bottom-up approach. Concentration-dependent uptake and cytotoxicity of PET NPs in macrophages are shown. The fabrication of well-characterized NPs, derived from high-commodity polymers, will support future studies to assess effects on biological systems.

Read via DOI Download PDF

Share this paper

Post Share Share Pin Email