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Ultraviolet-induced photodegradation elevated the toxicity of polystyrene nanoplastics on human lung epithelial A549 cells
Summary
Researchers found that UV-induced photodegradation significantly increased the toxicity of polystyrene nanoplastics on human lung epithelial cells. The degraded nanoplastics caused greater cell death, stronger oxidative stress, more severe membrane damage, and intensive mitochondrial dysfunction compared to non-degraded particles, suggesting that weathered nanoplastics in the environment may pose greater health risks than pristine ones.
UV-induced photodegradation posed greater cytotoxicity, as clearly evidenced by the impaired cell viability, stronger oxidative stress, serious membrane damage, intensive mitochondrial dysfunction, and the altered transcriptome responses.