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Article Tier 2 Detection Methods Environmental Sources Food & Water Human Health Effects Marine & Wildlife Remediation Reproductive & Development Sign in to save

Endocrine-Disrupting Compounds: An Overview on Their Occurrence in the Aquatic Environment and Human Exposure

Water 2021 233 citations

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This review examines how endocrine-disrupting compounds, including plastic-derived chemicals like phthalates and bisphenol A, accumulate in water sources worldwide. Researchers found these substances are now detectable even in drinking water, raising concerns about human exposure through the food chain. Several studies have linked exposure to these chemicals with reproductive and metabolic health issues, though more research is needed to fully understand the risks.

Body Systems
Models
Study Type Environmental

Endocrine-disrupting compounds (EDCs) as emerging contaminants have accumulated in the aquatic environment at concentration levels that have been determined to be significant to humans and animals. Several compounds belong to this family, from natural substances (hormones such as estrone, 17-estradiol, and estriol) to synthetic chemicals, especially pesticides, pharmaceuticals, and plastic-derived compounds (phthalates, bisphenol A). In this review, we discuss recent works regarding EDC occurrence in the aquatic compartment, strengths and limitations of current analytical methods used for their detection, treatment technologies for their removal from water, and the health issues that they can trigger in humans. Nowadays, many EDCs have been identified in significant amounts in different water matrices including drinking water, thus increasing the possibility of entering the food chain. Several studies correlate human exposure to high concentrations of EDCs with serious effects such as infertility, thyroid dysfunction, early puberty, endometriosis, diabetes, and obesity. Although our intention is not to explain all disorders related to EDCs exposure, this review aims to guide future research towards a deeper knowledge of EDCs’ contamination and accumulation in water, highlighting their toxicity and exposure risks to humans.

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