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Bisphenol A-an Overview on its Effect on Health and Environment

Biointerface Research in Applied Chemistry 2021 28 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Ramakrishna Mg, Agnishwar Girigoswami, Swati Chakraborty, Koyeli Girigoswami, C Metz, L Yang, Y Chen, Y Shen, M Yang, X Li, X Han, X Jiang, B Zhao, S Almeida, A Raposo, M Almeida-Gonzlez, C Carrascosa, Z Wang, H Cui, J Xia, Q Han, N Lv, J Gao, X Guo, F Zhang, J Ma, G Su, A Ahmad, L Huei, Y Huang, C Wong, J Zheng, H Bouwman, R Barra, B Wahlstrm, L Neretin, M Wong, A Bisphenol, E Gonzlez-Parra, J Herrero, U Elewa, R Bosch, A Ardun, J Egido, D Krieter, B Canaud, H Lemke, A Rodriguez, A Morgenroth, K Von Appen, G Dragoun, C Wanner, C Liao, K Kannan, N Osborne, R Cipelli, A Young, C Money, P Mccormack, R Luben, K.-T Khaw, N Wareham, A Shankar, S Teppala, C Sabanayagam, K Moriyama, T Tagami, T Akamizu, T Usui, M Saijo, N Kanamoto, Y Hataya, A Shimatsu, H Kuzuya, K Nakao, Y.-J Yang, Y.-P Hong, S Chae, A Rodrguez-Carrillo, V Mustieles, R Prez-Lobato, J Molina-Molina, I Reina-Prez, F Vela-Soria, S Rubio, N Olea, M Fernndez, C Zhou, W Wang, J Peretz, J Flaws, I Lang, T Galloway, A Scarlett, W Henley, M Depledge, R Wallace, D Melzer

Summary

This review synthesized evidence on bisphenol A (BPA) — a chemical used in polycarbonate plastics and epoxy resins — covering its sources of human exposure, endocrine-disrupting mechanisms, and associations with metabolic, reproductive, and developmental health outcomes.

Bisphenol A (BPA) is an organic material used to produce polycarbonate plastics and epoxy resins that are further used to make different plastic bottles and containers for packaging, storage, and food consumption. The possible leaching of BPA from the packaged food products can cause its migration to humans through the consumption of such foods. BPA is commonly known as primary endocrine disruptors that can mimic estrogen hormone action, thereby disrupting the normal estrogenic endocrine function. We have searched the relevant articles in PubMed and Google scholar to write this review and selected the appropriate articles to prepare the manuscript. There are reports on the adverse health effect of BPA on human health as well as in our environment. The routes of exposure of BPA in humans, plants, and aquatic animals were described. The effect on immune response, reproduction in animals and plants as well as neurotoxicity was elaborately discussed. In this review, we have discussed the use of BPA in dairy products and how it affects health and the environment.

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