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Co-exposure to Microplastics and Tire Particles Exacerbates Oxidative Stress and Gut Microbiome Dysbiosis in Zebrafish (Danio rerio)
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Physiological Alterations and Immune Modulation in Fish Exposed to Microplastics
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Researchers reviewed the physiological and immunological effects of microplastic exposure in fish, finding that these particles smaller than 5 mm induce a range of biological disruptions including immune modulation, oxidative stress, and systemic health impacts with broader implications for aquatic ecosystem integrity.
Co-exposure to microplastics and tire particles exacerbates oxidative stress and gut microbiome dysbiosis in zebrafish (Danio rerio)
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Researchers exposed zebrafish for 21 days to environmentally relevant mixtures of microplastics and tire particles and found that combined exposure caused more severe oxidative stress and gut microbiome disruption than either pollutant alone. Particle accumulation occurred mainly in the gut with secondary deposition in the liver, and the most pronounced tissue damage was observed under the highest combined exposure. Gut microbiota analysis revealed significant shifts in community structure, including reduced beneficial bacteria and increased pollutant-tolerant species.
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