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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Marine & Wildlife Remediation Sign in to save

The abundance of mRNA transcripts of bacteroidetal polyethylene terephthalate (PET) esterase genes may indicate a role in marine plastic degradation

2021 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Hongli Zhang, Robert F. Dierkes, Pablo Pérez-García, Sebastian Weigert, Stefanie Sternagel, Steven Hallam, Thomas Schott, Klaus Juergens, Christel Vollstedt, Cynthia Maria Chibani, Dominik Danso, Patrick C. F. Buchholz, Jürgen Pleiss, Alexandre Almeida, Birte Höcker, Ruth A. Schmitz, Jennifer Chow, Wolfgang R. Streit

Summary

Researchers discovered the first functional PET-degrading enzymes from the Bacteroidetes phylum of bacteria by analyzing gene expression in ocean environments. The finding suggests that this common group of marine bacteria may play a previously unrecognized role in breaking down PET plastic pollution in the ocean.

Polymers

Abstract Polyethylene terephthalate (PET) is an important synthetic polymer accumulating in nature 2 and recent studies have identified microorganisms capable of degrading PET. While the majority of 3 known PET hydrolases originate from the Actinobacteria and Proteobacteria, here we describe the 4 first functional PET-active enzymes from the Bacteroidetes phylum. Using a PETase-specific 5 Hidden-Markov-Model (HMM)-based search algorithm we identified two promiscuous and cold6 active esterases derived from Aequorivita sp. (PET27) and Chryseobacterium jeonii (PET30) acting 7 on PET foil and powder. Notably, one of the enzymes (PET30) was able to hydrolyze PET at 8 temperatures between 4° - 30°C with a similar turnover rate compared to the well-known Ideonella 9 sakaiensis enzyme (IsPETase). 10 PET27 and PET30 homologues were detected in metagenomes encompassing a wide range 11 of different global climate zones. Additional transcript abundance mapping of marine samples imply 12 that these promiscuous enzymes and source organisms may play a role in the long-term 13 degradation of microplastic particles and fibers.

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