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Effects of Microplastics on Immune Responses of the Yellow Catfish Pelteobagrus fulvidraco Under Hypoxia
Frontiers in Physiology2021
32 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 50
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Jie Wang
Liang Li,
Liang Li,
Lei Zhang,
Bo Li,
Elvis Genbo Xu,
Lingfeng Jiang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Youji Wang,
Youji Wang,
Menghong Hu,
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Youji Wang,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Ran Xu,
Liang Li,
Jie Wang
Jie Wang
Jie Wang
Menghong Hu,
Menghong Hu,
Elvis Genbo Xu,
Menghong Hu,
Elvis Genbo Xu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Elvis Genbo Xu,
Youji Wang,
Youji Wang,
Menghong Hu,
Menghong Hu,
Liang Li,
Elvis Genbo Xu,
Jie Wang
Elvis Genbo Xu,
Lingfeng Jiang,
Youji Wang,
Elvis Genbo Xu,
Menghong Hu,
Elvis Genbo Xu,
Lingfeng Jiang,
Menghong Hu,
Lingfeng Jiang,
Youji Wang,
Menghong Hu,
Youji Wang,
Elvis Genbo Xu,
Menghong Hu,
Elvis Genbo Xu,
Bo Li,
Elvis Genbo Xu,
Lei Zhang,
Elvis Genbo Xu,
Youji Wang,
Liang Li,
Jie Wang
Jie Wang
Jie Wang
Youji Wang,
Jie Wang
Jie Wang
Youji Wang,
Menghong Hu,
Menghong Hu,
Youji Wang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Menghong Hu,
Elvis Genbo Xu,
Man Wang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Jie Wang
Lei Zhang,
Lei Zhang,
Lei Zhang,
Lei Zhang,
Lei Zhang,
Lei Zhang,
Jie Wang
Youji Wang,
Bo Li,
Youji Wang,
Jie Wang
Menghong Hu,
Menghong Hu,
Youji Wang,
Youji Wang,
Menghong Hu,
Youji Wang,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Youji Wang,
Jie Wang
Youji Wang,
Menghong Hu,
Elvis Genbo Xu,
Youji Wang,
Jie Wang
Youji Wang,
Elvis Genbo Xu,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Youji Wang,
Elvis Genbo Xu,
Youji Wang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Menghong Hu,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Jie Wang
Youji Wang,
Jie Wang
Jie Wang
Bo Li,
Jie Wang
Jie Wang
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Elvis Genbo Xu,
Elvis Genbo Xu,
Youji Wang,
Youji Wang,
Youji Wang,
Jie Wang
Youji Wang,
Menghong Hu,
Jie Wang
Menghong Hu,
Youji Wang,
Menghong Hu,
Youji Wang,
Jie Wang
Liang Li,
Lei Zhang,
Jie Wang
Elvis Genbo Xu,
Jie Wang
Youji Wang,
Menghong Hu,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Youji Wang,
Jie Wang
Youji Wang,
Jie Wang
Elvis Genbo Xu,
Menghong Hu,
Menghong Hu,
Lei Zhang,
Menghong Hu,
Menghong Hu,
Youji Wang,
Youji Wang,
Youji Wang,
Jie Wang
Jie Wang
Menghong Hu,
Menghong Hu,
Menghong Hu,
Menghong Hu,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Menghong Hu,
Menghong Hu,
Elvis Genbo Xu,
Menghong Hu,
Menghong Hu,
Youji Wang,
Youji Wang,
Youji Wang,
Menghong Hu,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Youji Wang,
Youji Wang,
Elvis Genbo Xu,
Youji Wang,
Menghong Hu,
Youji Wang,
Jie Wang
Jie Wang
Youji Wang,
Youji Wang,
Jie Wang
Summary
Researchers found that polystyrene microplastics suppressed immune responses in yellow catfish under hypoxic conditions, with combined MP and low-oxygen exposure causing greater immunotoxicity than either stressor alone, relevant to freshwater aquaculture settings.
Compared with marine organisms, research on microplastics (MPs) in freshwater organisms is still less although MPs have been widely found in the freshwater ecosystem. Hypoxia is a ubiquitous issue in freshwater aquaculture, and under such scenarios, the toxic effects of MPs on typical aquaculture fish need to be clarified. In this study, we studied the effects of MPs (polystyrene) on specific growth rate (SGR), hypoxia-inducible factor-1α (HIF-1α), tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8), and interferon (IFN) in the yellow catfish (<i>Pelteobagrus fulvidraco</i>) under hypoxic conditions. After 15 days of exposure, the SGR was not affected by MPs or hypoxia. MPs significantly increased the expressions of HIF-1α and TNF-α but inhibited the expression of IFN at high concentration MPs under normoxia. However, hypoxia significantly inhibited the expression of IL-8 and TNF-α under high MP concentration and low MP concentration, respectively. In addition, MPs had significant concentration-dependent inhibitory effects on IFN under hypoxia. Surprisingly, a positive correction between HIF-1α and TNF-α was found in fish. Although hypoxia might alleviate the effects of MPs with low concentrations, the interaction of hypoxia and MPs aggravated the negative effects of MPs on immune factors at high concentration MPs. This study provided new insight into the complex effects of hypoxia and MPs on aquatic organisms, and future studies should focus on the cellular pathways of immune cells in fish. Given that MPs could induce the immune response in fish, considerations should be paid to the impacts of MPs on freshwater aquaculture, and hypoxia should be taken into consideration when evaluating the effects of MPs.