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Expression of Th17/Treg Cells in Peripheral Blood and Related Cytokines of Patients with Ulcerative Colitis of Different Syndrome Types and Correlation with the Disease
Summary
Researchers found that ulcerative colitis patients with damp-heat syndrome had the highest Th17/Treg imbalance in peripheral blood compared to other syndrome types, with higher Th17 ratios correlating with greater disease severity. These findings provide a quantitative basis for traditional Chinese medicine classification of UC severity.
There are differences in the expression of peripheral blood Th17/Treg cells and related cytokines among UC patients with different syndromes, and the damp-heat content is the most significant. The higher the ratio of Th17 cells in peripheral blood and the degree of Th17/Treg imbalance, the lower the ratio of Treg cells, and the more severe the condition of UC patients, which can provide a preliminary quantitative basis for the TCM classification and severity of the diagnosis of UC.
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