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Contribution of aged polystyrene microplastics to the bioaccumulation of pharmaceuticals in marine organisms using experimental and model analysis

Chemosphere 2021 19 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 45 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Yanqi Shi, Yanqi Shi, Yanqi Shi, Yanqi Shi, Yanqi Shi, Yanqi Shi, Peng Liu, Peng Liu, Peng Liu, Yanqi Shi, Xiaowei Wu, Peng Liu, Xiaowei Wu, Yanqi Shi, Yanqi Shi, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Yanqi Shi, Yanqi Shi, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Hanyu Wang, Hanyu Wang, Yanqi Shi, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Hexinyue Huang, Xiaowei Wu, Yanqi Shi, Hexinyue Huang, Hexinyue Huang, Yanqi Shi, Hexinyue Huang, Hexinyue Huang, Hexinyue Huang, Xiaowei Wu, Xiaowei Wu, Yanqi Shi, Hexinyue Huang, Hexinyue Huang, Hexinyue Huang, Hexinyue Huang, Yanqi Shi, Hanyu Wang, Hanyu Wang, Hanyu Wang, Huanhuan Shi, Huanhuan Shi, Hanyu Wang, Xiaowei Wu, Hexinyue Huang, Xiaowei Wu, Hexinyue Huang, Hexinyue Huang, Xiaowei Wu, Hexinyue Huang, Hexinyue Huang, Xiaowei Wu, Hexinyue Huang, Hexinyue Huang, Xiaowei Wu, Hexinyue Huang, Hexinyue Huang, Hexinyue Huang, Xiaowei Wu, Hexinyue Huang, Yanqi Shi, Shixiang Gao, Yanqi Shi, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Xiaowei Wu, Huanhuan Shi, Huanhuan Shi, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hexinyue Huang, Shixiang Gao Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Hanyu Wang, Xiaowei Wu, Yanqi Shi, Hexinyue Huang, Hexinyue Huang, Hexinyue Huang, Hanyu Wang, Hexinyue Huang, Yanqi Shi, Hanyu Wang, Yanqi Shi, Hexinyue Huang, Yanqi Shi, Yanqi Shi, Hexinyue Huang, Hanyu Wang, Yanqi Shi, Hexinyue Huang, Yanqi Shi, Hanyu Wang, Yanqi Shi, Yanqi Shi, Yanqi Shi, Hexinyue Huang, Hexinyue Huang, Xiaowei Wu, Hexinyue Huang, Yanqi Shi, Yanqi Shi, Hanyu Wang, Yanqi Shi, Shixiang Gao, Hexinyue Huang, Shixiang Gao, Hexinyue Huang, Yanqi Shi, Hexinyue Huang, Hexinyue Huang, Shixiang Gao, Hexinyue Huang, Hexinyue Huang, Shixiang Gao, Shixiang Gao, Shixiang Gao Hanyu Wang, Shixiang Gao Shixiang Gao Shixiang Gao Shixiang Gao Yanqi Shi, Yanqi Shi, Xiaowei Wu, Xiaowei Wu, Shixiang Gao Shixiang Gao, Shixiang Gao, Shixiang Gao, Shixiang Gao, Shixiang Gao Shixiang Gao Shixiang Gao Shixiang Gao, Shixiang Gao, Xiaowei Wu, Shixiang Gao, Shixiang Gao Shixiang Gao, Shixiang Gao Shixiang Gao Xiaowei Wu, Shixiang Gao, Yanqi Shi, Shixiang Gao Yanqi Shi, Yanqi Shi, Shixiang Gao, Yanqi Shi, Shixiang Gao, Shixiang Gao, Shixiang Gao

Summary

This study used experiments and bioaccumulation modeling to assess how weathered polystyrene microplastics affect pharmaceutical uptake in marine fish and seabirds, finding that aged MPs actually slightly reduced overall bioaccumulation of the drugs atorvastatin and amlodipine by acting as a sink, though warm-blooded animals still faced higher exposure risks than cold-blooded ones.

Polymers

Body Systems

Digestive

Study Type Environmental

Microplastics (MPs) in the environment would undergo extensive weathering, which can act as a vector affecting the accumulation of pollutants in organisms. However, the risk of organic pollutants adsorbed on aged MPs to marine organisms is poorly understood. This study revealed the contribution of aged polystyrene (PS) MPs to the total bioaccumulation of atorvastatin (ATV) and amlodipine (AML), and assessed the environmental risks via experimental and model analysis. The results showed that pharmaceuticals were more easily released in gastrointestinal fluids from aged MPs relative to that in simulated seawater. The hydrophobic pharmaceuticals were more bioaccessible than hydrophilic ones by organisms. Model analysis showed that ingestion of water and food were the most important uptake routes for pharmaceuticals in marine fish and seabirds, while aged PS MPs could decrease the bioaccumulation of pharmaceuticals (contributed for -2.9% and -1.2% for the total uptake of ATV, and -25.8% and -4.4% for AML), indicating the cleaning effect of aged MPs, and the potential higher exposure risks of pharmaceuticals in warm-blooded organisms than that in cold-blooded ones via ingested MPs. The study revealed the effect of aged MPs to the bioaccumulation of pharmaceuticals in marine organisms, and highlighted the combined risks of aged MPs and pharmaceuticals in the environment.

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