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Aggregate exposure pathways for microplastics (mpAEP): An evidence-based framework to identify research and regulatory needs

Water Research 2021 18 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 45 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Guyu Peng, Guyu Peng, Guyu Peng, Guyu Peng, Guyu Peng, Yan Lin, Guyu Peng, Daoji Li, Daoji Li, Guyu Peng, Bert van Bavel Guyu Peng, Guyu Peng, Guyu Peng, Guyu Peng, Guyu Peng, Guyu Peng, Yan Lin, Guyu Peng, Guyu Peng, Bert van Bavel Bert van Bavel Bert van Bavel Bert van Bavel Bert van Bavel Daoji Li, Daoji Li, Yan Lin, Yan Lin, Yan Lin, Yan Lin, Guyu Peng, Daoji Li, Bert van Bavel Daoji Li, Yan Lin, Bert van Bavel Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Guyu Peng, Bert van Bavel Bert van Bavel Daoji Li, Bert van Bavel Daoji Li, Daoji Li, Daoji Li, Daoji Li, Guyu Peng, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Bert van Bavel Bert van Bavel Bert van Bavel Bert van Bavel Bert van Bavel Guyu Peng, Guyu Peng, Guyu Peng, Guyu Peng, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Yan Lin, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Guyu Peng, Yan Lin, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Jinren Ni, Guyu Peng, Daoji Li, Daoji Li, Daoji Li, Daoji Li, You Song, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Guyu Peng, Daoji Li, Daoji Li, Bert van Bavel Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Yan Lin, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, You Song, Daoji Li, Bert van Bavel Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Bert van Bavel Daoji Li, Daoji Li, Daoji Li, Daoji Li, Yan Lin, Yan Lin, Jinren Ni, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Bert van Bavel Bert van Bavel Daoji Li, Daoji Li, Bert van Bavel Daoji Li, Yan Lin, Daoji Li, Yan Lin, Daoji Li, Yan Lin, Daoji Li, Daoji Li, Bert van Bavel Daoji Li, Daoji Li, Daoji Li, Yan Lin, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Daoji Li, Bert van Bavel Bert van Bavel Bert van Bavel Daoji Li, Guyu Peng, Bert van Bavel Bert van Bavel

Summary

An aggregate exposure pathway framework for microplastics was developed to organize and integrate fragmented data on microplastic sources, environmental levels, and toxicity in a way that supports human and ecological risk assessment, identifying critical research and data gaps.

Polymers

Microplastics as emerging contaminants have been detected from peaks to poles. High concerns on the risks of microplastic pollution to humans and ecosystems have therefore been raised in the past decade. While a large number of studies have been conducted to investigate the environmental levels and toxicity of microplastics, the information generated to support risk assessment is fragmented and the coherence between different types of study is largely lacking. Here we introduced the Aggregate Exposure Pathway (AEP), a conceptual framework originally proposed for chemical exposure assessment, to facilitate organization, visualization and evaluation of existing information generated from microplastic research, and to efficiently identify future knowledge and regulatory needs. A putative microplastic AEP network (mpAEP) was developed to demonstrate the concept and model development strategies. Two mpAEP case studies, with polyethylene (PE) as a prototype, were then presented based on existing environmental exposure data collected from the Changjiang Estuary and the East China Sea (Case I), and the Oslo Fjord (Case II), respectively. Weight of evidence (WoE) assessment of the mpAEPs were performed for evaluating the essentiality, theoretical plausibility, empirical evidence and quantitative understanding of the evidence and relationships in the AEPs. Both cases showed moderate/high WoE to support the strength of the models, whereas also displayed clear knowledge gaps, thus providing guidance for future investigations and regulations. The mpAEP framework introduced herein presents a novel strategy for organizing fragmented information from diverse types of microplastic research, enhancing mechanistic understanding of causal relationships and facilitating the development of quantitative prediction models for research and regulation in the future.

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