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Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana

Biomolecules 2022 20 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Ana Rita Rodrigues, Nélia C. Mestre, Tainá G. Fonseca, Paulo Pedro, Camilla Catarci Carteny, Bettie Cormier, Steffen Keiter, Maria João Bebianno

Summary

Researchers found that smaller polyethylene microplastics (4-6 µm) caused greater biomarker alterations in clam gills, while the digestive gland was more affected overall, suggesting particle size influences microplastic ecotoxicity in marine bivalves.

This study investigated the ecotoxicological effects of differently sized (4-6 µm and 20-25 µm) low-density polyethylene (LDPE) microplastics (MPs), with and without adsorbed benzo-a-pyrene (BaP), in clam Scrobicularia plana. Biomarkers of oxidative stress (superoxide dismutase-SOD; catalase-CAT), biotransformation (glutathione-S-transferases-GST), oxidative damage (lipid peroxidation-LPO) and neurotoxicity (acetylcholinesterase-AChE) were analysed in gills and digestive glands at different time intervals for a total of 14 days of exposure. In order to have a better impact perspective of these contaminants, an integrated biomarker response index (IBR) and Health Index were applied. Biomarker alterations are apparently more related to smaller sized (4-6 µm) MPs in gills and to virgin LDPE MPs in the digestive gland according to IBR results, while the digestive gland was more affected by these MPs according to the health index.

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