Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Gut & Microbiome Human Health Effects Sign in to save

The characteristics of dissolved organic matter release from UV-aged microplastics and its cytotoxicity on human colonic adenocarcinoma cells

The Science of The Total Environment 2022 64 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Peng Liu, Xuetao Guo Daofen Huang, Xuetao Guo Xuetao Guo Daofen Huang, Daofen Huang, Peng Liu, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Daofen Huang, Peng Liu, Daofen Huang, Yibo Xu, Yibo Xu, Daofen Huang, Peng Liu, Zhuozhi Ouyang, Peng Liu, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Daofen Huang, Daofen Huang, Zhuozhi Ouyang, Zhuozhi Ouyang, Daofen Huang, Xuetao Guo Xuetao Guo Hanzhong Jia, Hanzhong Jia, Peng Liu, Zhuozhi Ouyang, Xuetao Guo Peng Liu, Xuetao Guo Daofen Huang, Zhuozhi Ouyang, Zhuozhi Ouyang, Peng Liu, Daofen Huang, Daofen Huang, Peng Liu, Yibo Xu, Peng Liu, Peng Liu, Hanzhong Jia, Peng Liu, Hanzhong Jia, Daofen Huang, Yibo Xu, Yibo Xu, Yibo Xu, Hanzhong Jia, Daofen Huang, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Daofen Huang, Yibo Xu, Yibo Xu, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Xuetao Guo Zhuozhi Ouyang, Peng Liu, Peng Liu, Xuetao Guo Peng Liu, Xuetao Guo Peng Liu, Xuetao Guo Daofen Huang, Daofen Huang, Xuetao Guo Zhuozhi Ouyang, Xuetao Guo Xuetao Guo Peng Liu, Zhuozhi Ouyang, Zhuozhi Ouyang, Xuetao Guo Zhuozhi Ouyang, Xuetao Guo Zhuozhi Ouyang, Zhuozhi Ouyang, Peng Liu, Peng Liu, Xuetao Guo Yibo Xu, Peng Liu, Daofen Huang, Xuetao Guo Daofen Huang, Daofen Huang, Xuetao Guo Daofen Huang, Daofen Huang, Hanzhong Jia, Daofen Huang, Daofen Huang, Hanzhong Jia, Hanzhong Jia, Xuetao Guo Xuetao Guo Hanzhong Jia, Zhuozhi Ouyang, Hanzhong Jia, Hanzhong Jia, Xuetao Guo Zhuozhi Ouyang, Xuetao Guo Hanzhong Jia, Hanzhong Jia, Hanzhong Jia, Xuetao Guo Hanzhong Jia, Hanzhong Jia, Hanzhong Jia, Hanzhong Jia, Hanzhong Jia, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Peng Liu, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Zhuozhi Ouyang, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Hanzhong Jia, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Peng Liu, Peng Liu, Xuetao Guo Xuetao Guo Peng Liu, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Peng Liu, Xuetao Guo Xuetao Guo Xuetao Guo Zhuozhi Ouyang, Zhuozhi Ouyang, Hanzhong Jia, Xuetao Guo Xuetao Guo Hanzhong Jia, Xuetao Guo Hanzhong Jia, Xuetao Guo Hanzhong Jia, Hanzhong Jia, Zhuozhi Ouyang, Zhuozhi Ouyang, Hanzhong Jia, Zhuozhi Ouyang, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Zhuozhi Ouyang, Xuetao Guo Xuetao Guo Hanzhong Jia, Xuetao Guo Hanzhong Jia, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Hanzhong Jia, Hanzhong Jia, Xuetao Guo Zhuozhi Ouyang, Xuetao Guo Xuetao Guo Hanzhong Jia, Peng Liu, Hanzhong Jia, Xuetao Guo Xuetao Guo Peng Liu, Hanzhong Jia, Xuetao Guo Hanzhong Jia, Hanzhong Jia, Xuetao Guo Xuetao Guo Hanzhong Jia, Hanzhong Jia, Hanzhong Jia, Hanzhong Jia, Xuetao Guo Peng Liu, Xuetao Guo Hanzhong Jia, Peng Liu, Hanzhong Jia, Hanzhong Jia, Xuetao Guo Hanzhong Jia, Peng Liu, Hanzhong Jia, Zhuozhi Ouyang, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Hanzhong Jia, Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Xuetao Guo Hanzhong Jia, Xuetao Guo Xuetao Guo Xuetao Guo Hanzhong Jia, Xuetao Guo Hanzhong Jia, Xuetao Guo Hanzhong Jia, Xuetao Guo Xuetao Guo Xuetao Guo Hanzhong Jia, Hanzhong Jia, Hanzhong Jia, Xuetao Guo Xuetao Guo Hanzhong Jia, Hanzhong Jia, Xuetao Guo Xuetao Guo Hanzhong Jia, Xuetao Guo Xuetao Guo

Summary

Researchers investigated how UV-aged polyurethane microplastics release dissolved organic matter and its toxic effects on human colon cells. They found that the concentration of released organic matter increases with longer aging time, and its cytotoxicity also increases accordingly, with air-aged microplastics releasing more than water-aged ones. The study suggests that weathered microplastics may pose growing health concerns as they release increasing amounts of potentially harmful organic compounds over time.

Polymers

Body Systems

Digestive

Study Type In vitro

There are a large number of microplastic (MPs) in the sea or on land, most of which undergo physical, chemical or biological processes leading to the release of dissolved organic matter (DOM). In this study, we analyzed the change of Polyurethane microplastic (PU-MPs) valence bond under different aging conditions thanks to Fourier transform infrared spectroscopy (FTIR) and its surface characteristics using scanning electron microscopy (SEM) and also described the characteristics of DOM dissolved from PU (PU-DOM) under UV aging process in two different medium (water and air), based on Dissolved organic carbon (DOC) measurements, UV-visible spectrometer and Three-dimensional excitation emission matrices (3D-EEMs). The DOC data both showed that Under UV aging of different systems, PU-DOM concentration increases with the extension of aging time, and correspondingly, its toxicity to human colon adenocarcinoma cells also increases, but the release amount of PU-DOM under air aging is higher than that of PU-DOM in water. We speculate that it may be the refraction and scattering of water, which leads to the reduction of the intensity of UV radiation. 3D-EEMs identified tryptophan-like fluorescent component and tyrosine-like component, meanwhile, the liquid chromatography-mass spectrometer (LC-MS) data further confirmed the formation of acid substances. The results further confirmed that the composition of PU-DOM in different systems is the same, but the release amount is different. The contents of the produced conjugated carbonyls and Reactive oxygen species (ROS) because of light irradiation increased likewise. The cytotoxicity of PU-DOM was consistent with the changing trend of ROS level in PU-MPs, suggesting that the produced ROS induced the in vitro toxicities. The results not only highlight the adverse health effects of photoaged PU-MPs, but also provide new perspectives for the environmental risks of MPs.

Read via DOI PubMed

Share this paper

Post Share Share Pin Email