We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Intergenerational and biological effects of roxithromycin and polystyrene microplastics to Daphnia magna
AI summary Read the abstract
Researchers studied the intergenerational effects of the antibiotic roxithromycin combined with polystyrene microplastics on water fleas (Daphnia magna) across multiple generations. They found that UV-aged microplastics altered the carrier effects on the antibiotic compared to pristine particles, changing survival and reproductive outcomes. The study suggests that the aging and weathering state of microplastics in the environment influences how they interact with pharmaceutical pollutants and their combined toxicity.
The influence of microplastics (MPs) on transgenerational effects of pharmaceuticals are drawing growing attention, however, whether aged process will alter the carrier effects of MPs were unknown. In this study, the intergenerational toxicity of single and combined exposure of polystyrene microplastics (PS-MPs) and roxithromycin (ROX) were investigated at the environmentally related concentrations, using Daphina magna as test organism. In the presence of UV-aged PS-MPs, the survival of D. magna for maternal generation (F0) at ROX concentration of 0.1 and 10 µg/L were increased by 20% and 40%, respectively. Meanwhile, the inhibition effects of ROX on the number of offspring and intrinsic rate of natural increase were obviously moderated. All these reproductive toxicity of ROX and PS-MPs in the first offspring (F1) were further aggravated both for the single and combined exposure. And the adverse effects disappeared much easier for the single exposure compared to the co-exposure through subsequent recovery. The combined exposure resulted in the change of inhibition of ROX on the swimming velocity and acceleration of D. magna into induction, while the feeding behavior kept inhibited. The AChE activity was distinctly increased by 1.61-3.25 times for the single and combined treatments, and the induction level of UV-aged MPs was higher than that of original MPs. Oxidative stress of the single exposure of ROX and original PS-MPs was observed with obvious induction of T-AOC and SOD activity, while the significant increase of MDA content was observed for the co-exposure. Among all indicators, the biochemical biomarkers and time of first brood were attributed to a class among all indicators, indicating that the time of first brood might be the most sensitive reproductive toxicity index. These results illustrated that both maternal impacts and offspring quality need to be considered for assessment of interaction of emerging contaminants.
More Papers Like This
Multigenerational Toxicity of Weathered Microplastic Fibres Carrying Pharmaceutical Residues in Freshwater Zooplankton Communities
AI summary Read the abstract
A lab simulation exposed freshwater zooplankton across multiple generations to weathered microplastic fibers combined with pharmaceutical residues. Survival and other health measures worsened with each generation, and the combination of microplastics and drug residues caused more harm than either contaminant alone.
Interactive effects of microplastics and selected pharmaceuticals on red tilapia: Role of microplastic aging
AI summary Read the abstract
Researchers compared how aged versus virgin polystyrene microplastics interact with the antibiotic sulfamethoxazole and the beta-blocker propranolol in red tilapia. They found that aged microplastics, which have rougher surfaces from UV weathering, adsorbed more pharmaceuticals and altered their bioavailability to the fish. The study demonstrates that environmental aging of microplastics changes their capacity to carry and release pharmaceutical contaminants in aquatic systems.
First insight of the intergenerational effects of tri-n-butyl phosphate and polystyrene microplastics to Daphnia magna
AI summary Read the abstract
Researchers studied the combined effects of polystyrene microplastics and the flame retardant tributyl phosphate on water fleas across multiple generations. They found that co-exposure caused more severe impacts on survival, growth, and reproduction than either contaminant alone, with effects persisting into subsequent generations. The study suggests that microplastics carrying adsorbed chemicals may pose compounding risks to aquatic organisms over time.
Combined exposure of polystyrene microplastics and carbamazepine induced transgenerational effects on the reproduction of Daphnia magna
AI summary Read the abstract
Researchers found that combined exposure to polystyrene microplastics and the pharmaceutical carbamazepine caused transgenerational reproductive toxicity in water fleas, with the second generation showing significantly reduced offspring numbers and disrupted expression of reproduction-related genes.
Short-term and long-term effects of microplastics and organic UV-filters on the invertebrate model species Daphnia magna
AI summary Read the abstract
Researchers exposed water fleas to polystyrene microplastics, a mixture of UV-filter chemicals found in sunscreens, or both over 21 days. The microplastics alone reduced body size and reproduction, while combined exposure with UV-filters further impaired swimming behavior and offspring production. The study highlights that microplastics and common personal care product chemicals can interact to create compounding negative effects on freshwater organisms.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.