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Comment on “Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status”
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This comment raised methodological concerns about a study reporting that fecal microplastics correlate with inflammatory bowel disease status, questioning whether the plastic detection methods adequately controlled for contamination and whether the patient and control groups were sufficiently matched. The authors called for improved standardization in human microplastic exposure studies.
ADVERTISEMENT RETURN TO ISSUEPREVCorrespondence/Rebut...Correspondence/RebuttalNEXTComment on "Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status"Ran Fujimoto*Ran FujimotoDepartment of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo, Kyoto 6068501, Japan*Email: [email protected]More by Ran Fujimotohttps://orcid.org/0000-0002-9070-1956, Kouji H. HaradaKouji H. HaradaDepartment of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Yoshida Konoe, Sakyo, Kyoto 6068501, JapanMore by Kouji H. Haradahttps://orcid.org/0000-0001-7319-123X, and Mutsuko MinataMutsuko MinataResearch Institute, Nozaki Tokushukai Hospital, 10-50, 2-chome, Tanigawa, Daito, Osaka 574-0074, JapanMore by Mutsuko MinataCite this: Environ. Sci. Technol. 2022, 56, 17, 12778Publication Date (Web):August 24, 2022Publication History Received19 June 2022Published online24 August 2022Published inissue 6 September 2022https://pubs.acs.org/doi/10.1021/acs.est.2c04391https://doi.org/10.1021/acs.est.2c04391article-commentaryACS PublicationsCopyright © 2022 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views2107Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (911 KB) Get e-AlertscloseSUBJECTS:Bacteria,Dietary fiber,Food,Inflammation,Testing and assessment Get e-Alerts
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Response to Comment on “Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status”
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This correspondence responded to critiques of a study reporting a correlation between fecal microplastic concentrations and inflammatory bowel disease status in human patients. The authors defended their analytical methods and argued that the observed association warrants further investigation into microplastics as a potential factor in gut inflammation.
Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status
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Researchers found higher concentrations and greater diversity of microplastics in fecal samples from inflammatory bowel disease patients compared to healthy controls, suggesting a potential association between microplastic ingestion and gut inflammation, though causality remains to be established.
Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status
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Researchers analyzed microplastics in the stool of patients with inflammatory bowel disease (IBD) and healthy volunteers, finding that IBD patients had significantly higher concentrations of microplastics in their feces. PET plastic and polyamide were the most common types found, likely originating from food packaging and dust. The positive correlation between microplastic levels and IBD severity suggests that microplastic exposure may be linked to gut inflammation, though it is not yet clear whether the plastics contribute to the disease or the disease causes more plastic retention.
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