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The electronic tree of life (eToL): a net of long probes to characterize the microbiome from RNA-seq data

BMC Microbiology 2022 11 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 35 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Xinyue Hu, Jürgen Haas, Jürgen Haas, Richard Lathe Richard Lathe

Summary

Researchers developed the electronic Tree of Life (eToL), a tool that uses long RNA probes to identify and characterize the full range of microbes living in a sample from standard RNA-sequencing data. This method broadens the ability to study the microbiome — the community of microorganisms in a given environment — with potential uses in diagnostics and environmental monitoring.

This generic methodology is likely to find wide application in microbiome analysis including diagnostics.

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