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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Nanoplastics Sign in to save

Metabolomics-based analysis in Daphnia magna after exposure to low environmental concentrations of polystyrene nanoparticles

Environmental Science Nano 2023 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Egle Kelpsiene, Tommy Cedervall, Anders Malmendal

Summary

Daphnia magna exposed to low environmental concentrations of polystyrene nanoplastics (as low as 3.2 micrograms per liter) showed significant metabolic disruptions detectable by metabolomics analysis. Carboxylate-functionalized particles caused distinct metabolic responses compared to amine-functionalized particles, suggesting surface chemistry drives differential toxicity.

Polymers
Models

Particles used in the study: 53 nm PS-NH 2 and 62 nm PS-COOH. Significant metabolic responses at: 3.2 μg L −1 PS NPs.

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