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Article
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Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
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Wistar Rats Hippocampal Neurons Response to Blood Low-Density Polyethylene Microplastics: A Pathway Analysis of SOD, CAT, MDA, 8-OHdG Expression in Hippocampal Neurons and Blood Serum Aβ42 Levels
Neuropsychiatric Disease and Treatment
2023
27 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 55
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Tri Marthy Mulyasari,
Soedjajadi Keman
Soedjajadi Keman,
Soedjajadi Keman,
Lilis Sulistyorini,
Yudhiakuari Sincihu,
Yudhiakuari Sincihu,
Soedjajadi Keman
Yudhiakuari Sincihu,
Yudhiakuari Sincihu,
Tri Marthy Mulyasari,
Yudhiakuari Sincihu,
Tri Marthy Mulyasari,
Yudhiakuari Sincihu,
Yudhiakuari Sincihu,
Soedjajadi Keman,
Yudhiakuari Sincihu,
Yudhiakuari Sincihu,
Soedjajadi Keman,
Soedjajadi Keman
Saliza Mohd Elias,
I Ketut Sudiana,
Soedjajadi Keman
Muhammad Farid Dimjati Lusno,
Yudhiakuari Sincihu,
I Ketut Sudiana,
I Ketut Sudiana,
Lilis Sulistyorini,
Lilis Sulistyorini,
Lilis Sulistyorini,
Tri Marthy Mulyasari,
Kurnia Kusumastuti,
Tri Marthy Mulyasari,
Lilis Sulistyorini,
Soedjajadi Keman,
Soedjajadi Keman
Saliza Mohd Elias,
Tri Marthy Mulyasari,
Yudhiakuari Sincihu,
Saliza Mohd Elias,
Lilis Sulistyorini,
I Ketut Sudiana,
Muhammad Farid Dimjati Lusno,
Kurnia Kusumastuti,
Tri Marthy Mulyasari,
Saliza Mohd Elias,
Lilis Sulistyorini,
Soedjajadi Keman,
Soedjajadi Keman
Summary
Researchers investigated the effects of blood-borne low-density polyethylene microplastics on hippocampal neurons in Wistar rats. Pathway analysis showed that microplastic particles in the blood significantly affected hippocampal neurons, with changes observed in oxidative stress markers SOD, CAT, MDA, and 8-OHdG expression as well as blood serum amyloid-beta 42 levels.
The pathway analysis showed that hippocampal neurons were significantly affected by microplastic particles in the blood.
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