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Wistar Rats Hippocampal Neurons Response to Blood Low-Density Polyethylene Microplastics: A Pathway Analysis of SOD, CAT, MDA, 8-OHdG Expression in Hippocampal Neurons and Blood Serum Aβ42 Levels

Neuropsychiatric Disease and Treatment 2023 27 citations

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Researchers investigated the effects of blood-borne low-density polyethylene microplastics on hippocampal neurons in Wistar rats. Pathway analysis showed that microplastic particles in the blood significantly affected hippocampal neurons, with changes observed in oxidative stress markers SOD, CAT, MDA, and 8-OHdG expression as well as blood serum amyloid-beta 42 levels.

Polymers
Body Systems
Models

The pathway analysis showed that hippocampal neurons were significantly affected by microplastic particles in the blood.

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