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Repair mechanism of Yishen Tongluo formula on mouse sperm DNA fragmentation caused by polystyrene microplastics
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This study investigated a traditional Chinese medicine formula (Yishen Tongluo) for its potential to repair sperm DNA damage caused by polystyrene microplastics. Researchers found that the formula's protective mechanism may be associated with the PI3K/Akt signaling pathway and the protein SPARC. The study suggests a new direction for using traditional medicine approaches to address reproductive system injury linked to microplastic exposure.
The precise mechanism by which YSTL inhibits PD-MPs DNA damage may be associated with the PI3K/Akt pathway and SPARC. It provides a new direction for using traditional Chinese medicine to prevent and repair reproductive system injury caused by MPs.
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Protective effect of Cordycepin on blood-testis barrier against pre-puberty polystyrene nanoplastics exposure in male rats
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Young male rats exposed to polystyrene nanoplastics during a critical growth period developed lasting damage to their reproductive system, including lower sperm quality and weakened barriers protecting developing sperm cells. A natural compound called cordycepin partially reversed this damage by reducing inflammation and oxidative stress, suggesting possible protective strategies against reproductive harm from plastic pollution.
Pinostrobin alleviates testicular and spermatological damage induced by polystyrene microplastics in adult albino rats
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Researchers found that pinostrobin, a natural flavonoid, alleviated testicular damage and sperm abnormalities induced by polystyrene microplastics in rats, suggesting it may be a potential therapeutic candidate for microplastic-related reproductive toxicity.
The potential protective roles of Astragalus polysaccharides against toxicity of polystyrene nanoplastics on mice sperm exposed
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Tiny plastic particles (nanoplastics) harmed sperm quality and testosterone levels in mice, but a natural plant compound called Astragalus polysaccharides largely reversed this damage. While this study was done in mice, not humans, it suggests certain plant-based supplements might one day help protect fertility from everyday plastic exposure.
Clinical study on the treatment of male infertility with Wuwei Fuzheng Yijing decoction based on microplastics: Study protocol for a randomized controlled trial
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This clinical trial protocol describes a study testing a traditional Chinese medicine treatment for male infertility, with a focus on reducing microplastic levels in semen. It aims to explore whether microplastics in reproductive fluids contribute to fertility problems and whether targeted treatment can help.
Rhamnetin alleviates polystyrene microplastics-induced testicular damage by restoring biochemical, steroidogenic, hormonal, apoptotic, inflammatory, spermatogenic and histological profile in male albino rats
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Researchers studied whether the plant compound rhamnetin could protect against testicular damage caused by polystyrene microplastics in rats. Microplastic exposure caused significant harm to sperm quality, hormone levels, and testicular tissue through oxidative stress and inflammation. Co-treatment with rhamnetin restored many of these markers, suggesting it may help counteract some of the reproductive harm associated with microplastic exposure.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.