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Intrinsically Disordered Synthetic Polymers in Biomedical Applications

Polymers 2023 13 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 40 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Elif Yüce, Abraham J. Domb, Haytam Kasem, Vladimir N. Uversky, Orkid Coskuner‐Weber

Summary

This is a polymer chemistry review on intrinsically disordered synthetic polymers designed to mimic flexible proteins for biomedical applications like drug delivery and organ transplants; it is not a microplastics research paper.

Body Systems

In biology and medicine, intrinsically disordered synthetic polymers bio-mimicking intrinsically disordered proteins, which lack stable three-dimensional structures, possess high structural/conformational flexibility. They are prone to self-organization and can be extremely useful in various biomedical applications. Among such applications, intrinsically disordered synthetic polymers can have potential usage in drug delivery, organ transplantation, artificial organ design, and immune compatibility. The designing of new syntheses and characterization mechanisms is currently required to provide the lacking intrinsically disordered synthetic polymers for biomedical applications bio-mimicked using intrinsically disordered proteins. Here, we present our strategies for designing intrinsically disordered synthetic polymers for biomedical applications based on bio-mimicking intrinsically disordered proteins.

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