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Assessment of microplastic contamination in an eastern Pacific tuna (Katsuwonus pelamis) and evaluation of its health risk implication through molecular docking and metabolomics studies

Food Chemistry 2023 6 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Danyun Ou, Weiwen Li, Zhong Pan Rupeng Du, Lijun Wu, Zhong Pan Zhong Pan Rupeng Du, Rupeng Du, Zhong Pan Zhong Pan Zhong Pan Lijun Wu, Zhong Pan Zhong Pan Haitao Lin, Rupeng Du, Haitao Lin, Zhong Pan Xiaojie Dai, Haitao Lin, Zhong Pan Haitao Lin, Zhong Pan Rupeng Du, Xiaojie Dai, Rupeng Du, Jing Xu, Jing Xu, Haitao Lin, Haitao Lin, Jing Xu, Weiwen Li, Weiwen Li, Weiwen Li, Weiwen Li, Haitao Lin, Zhong Pan Rupeng Du, Haitao Lin, Danyun Ou, Lei Wang, Rupeng Du, Weiwen Li, Hui Lin, Hui Lin, Lijun Wu, Weiwen Li, Zhong Pan Hui Lin, Lijun Wu, Xiaojie Dai, Jing Xu, Zhong Pan Xiaojie Dai, Lijun Wu, Zhong Pan Zhong Pan Lijun Wu, Zhong Pan Weiyi He, Haitao Lin, Hao Huang, Haitao Lin, Zhong Pan Rupeng Du, Danyun Ou, Hao Huang, Hui Lin, Weiwen Li, Xiaojie Dai, Zhong Pan

Summary

Researchers found microplastic contamination across multiple organs of skipjack tuna from the Eastern Pacific, with molecular docking and metabolomics analyses revealing potential health risks from microplastic-associated chemical exposure through seafood consumption.

Polymers

PE PET

Body Systems

Musculoskeletal

This work investigated microplastic (MP) pollution in a commercially-important tuna species Katsuwonus pelamis (K. pelamis) from the Eastern Pacific and health implications. 125 MPs were extracted from gills, esophagus, stomachs, intestinal tracts, and muscle of K. pelamis. MPs in the esophagus was the highest, ∼7.6 times higher than that in the gill. Polyester and polyethylene terephthalate (PET) were dominant. Molecular docking implied that PET stabilized the complex via forming 4 new hydrogen bonds that interacted with Arg83, Gln246, Thr267, and Gly268, given that PET can enter glycerol kinase protein active pocket. Metabonomic results suggested that Glycerol 3-phosphate up expressed 1.66 more times that of control groups with no MPs in the muscle. This confirmed that MPs would lie in the glycerol kinase protein active pocket, which triggered menace to K. pelamis. The results provided insights into suggested the potential influence of MPs on the sustainability of fisheries and seafood safety.

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