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Serratia marcescens in the intestine of housefly larvae inhibits host growth by interfering with gut microbiota
Summary
Using bacteriophages to manipulate Serratia marcescens abundance in housefly larvae guts, researchers found that this bacterium inhibits larval growth by interfering with normal gut flora balance and nutrient assimilation, highlighting the critical role of intestinal microbiota in insect development.
In our study, using phage as a tool to regulate the abundance of S. marcescens, we highlighted the mechanism by which S. marcescens inhibits the growth and development of housefly larvae and illustrated the importance of intestinal flora for larval development. Furthermore, by studying the dynamic diversity and variation in gut bacterial communities, we improved our understanding of the possible relationship between the gut microbiome and housefly larvae when houseflies are invaded by exogenous pathogenic bacteria.
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