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CompRanking_database
Summary
This entry describes CompRanking, a curated database for analyzing antimicrobial resistance genes, including those found in plastisphere microbiomes living on plastic debris. Plastic surfaces in the ocean act as hotspots for antibiotic-resistant bacteria, making this database a useful tool for tracking that risk.
CompRanking alignment database version 1.1. CompRanking is with a curated alignment database designed to support comparative analysis of antimicrobial resistance genes (ARGs) in various environments, including the plastic-associated microbiomes (the "Plastisphere"). This version (1.1) includes updated sequence alignments and annotations relevant to the study of ARGs across both biodegradable and nonbiodegradable microplastic environments. This database is affiliated with our peer-reviewed research article published in Environmental Science & Technology (ES&T): Determining Antimicrobial Resistance in the Plastisphere: Lower Risks of Nonbiodegradable vs Higher Risks of Biodegradable MicroplasticsDOI: 10.1021/acs.est.5c00246 In this study, we utilized the CompRanking database to benchmark and compare resistome profiles associated with different types of microplastics. The findings highlight the potential environmental risks posed by biodegradable plastics due to higher associations with ARGs, compared to conventional nonbiodegradable plastics. Citation: If you use this database in your research, please cite our article: Luo, Gaoyang, et al. "Determining Antimicrobial Resistance in the Plastisphere: Lower Risks of Nonbiodegradable vs Higher Risks of Biodegradable Microplastics." Environmental Science & Technology 59.15 (2025): 7722-7735. https://doi.org/10.1021/acs.est.5c00246
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