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Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of salidroside on intestine ischemia reperfusion
Summary
Researchers investigated the therapeutic mechanism of salidroside for intestinal ischemia-reperfusion injury using network pharmacology and experimental validation, finding that it may target AMPK and TXNIP domains to provide protective effects.
SAL may target AMPK and TXNIP domains to act as a therapeutic agent for intestinal IR. These findings comprehensively reveal the potential therapeutic targets for SAL against intestinal IR and provide theoretical basis for the clinical application of SAL in the treatment of intestinal IR.
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