P17-17: Polystyrene microplastic affects the hepatic antioxidant and detoxifying systems in subchronically exposed gilthead seabream (Sparus aurata)

Polyethylene Microplastics Induce Concentration- and Time-Dependent Hematophysiological Impairment and Oxidative Stress Following Tissue Accumulation in Rock Bream (Oplegnathus Fasciatus)

Gauging the effects of a chronic exposure to polystyrene nanoplastics in the liver and intestine of Carassius auratus

New Insights into the Effects of Polystyrene Microplastics on Freshwater Fish, Labeo rohita: Assessment on Histopathology, Mineral Composition, Bioaccumulation and Antioxidant Activity

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Researchers fed Labeo rohita fish diets containing up to 2.5% polystyrene microplastics over 90 days and found dose-dependent intestinal damage, reduced antioxidant enzyme activity, altered mineral composition in muscle tissue, and bioaccumulation of particles, suggesting risks to farmed fish health and potentially to people who consume them.

Oxidative damage and intestinal microbial imbalance induced by polystyrene microplastics and cadmium in zebrafish (Danio rerio)

Subchronic oral exposure to polystyrene microplastics affects hepatic lipid metabolism, inflammation, and oxidative balance in gilthead seabream (Sparus aurata)

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Gilthead seabream fed polystyrene microplastics for 21 days developed signs of liver damage including fat buildup, inflammation, and oxidative stress -- changes similar to early-stage fatty liver disease. Since fish liver responds to microplastics in ways comparable to mammalian livers, these findings raise concerns about what chronic microplastic exposure might do to liver health in humans and other animals.