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Nanoplastics
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Compound effect and mechanism of oxidative damage induced by nanoplastics and benzo [a] pyrene
Journal of Hazardous Materials2023
17 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 55
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Huijian Shi,
Yaoyue Wang,
Yaoyue Wang,
Ning Sun,
Shuqi Guo,
Ning Sun,
Ning Sun,
Xiangxiang Li,
Huijian Shi,
Yaoyue Wang,
Yaoyue Wang,
Huijian Shi,
Xiangxiang Li,
Xiangxiang Li,
Ning Sun,
Xiangxiang Li,
Ning Sun,
Ning Sun,
Ning Sun,
Shuqi Guo,
Huijian Shi,
Jinhu Wang,
Huijian Shi,
Huijian Shi,
Huijian Shi,
Huijian Shi,
Shaoyang Hu,
Shaoyang Hu,
Ning Sun,
Shaoyang Hu,
Shuqi Guo,
Shuqi Guo,
Shaoyang Hu,
Shuqi Guo,
Yaoyue Wang,
Huijian Shi,
Huijian Shi,
Huijian Shi,
Huijian Shi,
Huijian Shi,
Shuqi Guo,
Shuqi Guo,
Yaoyue Wang,
Xiangxiang Li,
Huijian Shi,
Shaoyang Hu,
Huijian Shi,
Shuqi Guo,
Rutao Liu
Huijian Shi,
Shaoyang Hu,
Huijian Shi,
Shuqi Guo,
Shuqi Guo,
Xiangxiang Li,
Huijian Shi,
Xiangxiang Li,
Shuqi Guo,
Shuqi Guo,
Shuqi Guo,
Xiangxiang Li,
Canzhu Gao,
Rutao Liu
Xiangxiang Li,
Xiangxiang Li,
Xiangxiang Li,
Canzhu Gao,
Canzhu Gao,
Canzhu Gao,
Canzhu Gao,
Shaoyang Hu,
Shaoyang Hu,
Xiangxiang Li,
Canzhu Gao,
Canzhu Gao,
Canzhu Gao,
Xiangxiang Li,
Yaoyue Wang,
Xiangxiang Li,
Shaoyang Hu,
Shuqi Guo,
Rutao Liu
Shuqi Guo,
Rutao Liu
Shuqi Guo,
Shuqi Guo,
Yaoyue Wang,
Rutao Liu
Ning Sun,
Rutao Liu
Rutao Liu
Yaoyue Wang,
Rutao Liu
Shaoyang Hu,
Rutao Liu
Shaoyang Hu,
Rutao Liu
Rutao Liu
Rutao Liu
Shuqi Guo,
Rutao Liu
Rutao Liu
Rutao Liu
Shaoyang Hu,
Shuqi Guo,
Rutao Liu
Rutao Liu
Xiangxiang Li,
Xiangxiang Li,
Yaoyue Wang,
Yaoyue Wang,
Shuqi Guo,
Shuqi Guo,
Yaoyue Wang,
Rutao Liu
Xiangxiang Li,
Xiangxiang Li,
Rutao Liu
Shaoyang Hu,
Shaoyang Hu,
Rutao Liu
Rutao Liu
Xiangxiang Li,
Xiangxiang Li,
Shuqi Guo,
Canzhu Gao,
Shaoyang Hu,
Rutao Liu
Canzhu Gao,
Shuqi Guo,
Shuqi Guo,
Rutao Liu
Shaoyang Hu,
Xiangxiang Li,
Rutao Liu
Shuqi Guo,
Canzhu Gao,
Ning Sun,
Canzhu Gao,
Rutao Liu
Shaoyang Hu,
Shaoyang Hu,
Rutao Liu
Shaoyang Hu,
Rutao Liu
Rutao Liu
Rutao Liu
Rutao Liu
Rutao Liu
Rutao Liu
Rutao Liu
Shaoyang Hu,
Rutao Liu
Summary
Researchers examined how polystyrene nanoplastics and a common environmental pollutant called benzo[a]pyrene work together to cause oxidative damage in earthworm cells. They found that the two contaminants had a synergistic toxic effect, with combined exposure producing significantly higher levels of cell-damaging reactive oxygen species than either pollutant alone. The study suggests that nanoplastics may enhance the harmful effects of other soil pollutants by altering how they interact with living cells.
Nanoplastics and polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in soil environments. In order to objectively evaluate the toxic interaction between polystyrene nanoplastics (PS NPs) and benzo [a] pyrene (BaP), oxidative damage at the level of earthworm cells and biomacromolecules was investigated by experiments combined with molecular dynamics simulation. Studies on cells reveal that PS NPs and BaP had synergistic toxicity when it came to causing oxidative stress. Cellular reactive oxygen species (ROS) levels under combined pollutant exposure were 24% and 19% higher, respectively than when PS NPs and BaP were exposed alone (compared to the blank group). In addition, BaP and PS NPs inhibited the ability of CAT to decompose HO by affecting the structure of the proximal amino acid Tyr 357 in the active center of CAT, which exacerbated oxidative stress to a certain extent. Therefore, the synergistic toxic effect of BaP and PS NPs is due to the mutual complement of the two to the induction of protein structural looseness, and the strengthening of the stability of the conjugate (CAT-BaP-PS) under the weak interaction. This work provides a new perspective and approach on how to talk about the toxicity of combined pollutants.