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Detection and quantification of various microplastics in human endometrium based on laser direct infrared spectroscopy
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For the first time, researchers detected microplastics in human uterine lining tissue, finding 13 different types of plastic particles in the samples. Most particles were very small (under 100 micrometers), and certain habits like drinking from plastic bottles and chewing gum were linked to higher microplastic levels. This raises concerns about potential effects on reproductive health and fertility, though more research is needed.
The pollution of microplastics (MPs) has received widespread attention with the increasing usage of plastics in recent years. MPs could enter the human body and exist in the circulatory system. Endometrium, with rich blood vessels, acts as an essential role in human health and female fertility. However, there is no study reporting the MPs exposure in human endometrium. We collected the endometrium samples to detect the presence of MPs qualitatively and quantitatively via laser direct infrared. We found that there was a total of 13 types of MPs existing in the collected samples, among which 6 special types of MPs were with both high abundance and high detection rate. The abundance of these MPs ranged from 0 to 117 particles/100 mg, with a median abundance of 21 particles/100 mg. Most detected MPs, accounting for 88.35 %, were in small size (20-100 μm). Among small-size MPs, ethylene-acrylic acid copolymer ranked first while polyethylene accounted for the largest proportion among large-size MPs (100-500 μm). Correlation analysis indicated there was no significant relationship between age and MP abundance or BMI and MP abundance. We also designed a questionnaire to investigate lifestyle and daily habits, aiming at revealing the potential relationship between MP exposure and living habits. We discovered that some drinking habits and chewing gum were significantly correlated with a higher level of MP exposure. For the first time, we identified the presence of MPs in human endometrium and clarified the potential connections between MP exposure and lifestyle. Further studies are still necessary to explore more underlying information.
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