Comparative hepatotoxicity of four common food-contact microplastics in mice: oxidative stress, inflammation, and tryptophan metabolism disorder

The toxicity of polyethylene microplastics on molecular and biochemical parameters in albino mice

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Researchers assessed the molecular and biochemical effects of polyethylene microplastic exposure in albino mice, finding dose-dependent toxicity across multiple organ systems, with measurable alterations in liver enzymes, oxidative stress markers, and blood cell parameters consistent with systemic health impacts.

Cellular and Animal Toxicities of Micro- and Nanoplastics

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Researchers reviewed evidence from cell and animal studies on the toxic effects of micro- and nanoplastics, finding that these particles can cause inflammation, oxidative stress, and organ damage in laboratory models, raising concern about what chronic low-level human exposure might mean for long-term health.

Stress (Cortisol) and Hepatotoxic Effects of Polystyrene Micro- and Nanoplastics in Swiss Albino Mice: A Comparative Study

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Researchers exposed Swiss albino mice to polystyrene micro- and nanoplastics and compared the stress and liver toxicity responses, finding that both sizes elevated cortisol levels and caused hepatotoxic damage, with nanoplastics generally producing more pronounced physiological disruption than microplastics.

Microplastics and nanoplastics in human health: a comprehensive review of exposure pathways, cellular mechanisms, and toxicological implications

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Researchers reviewed human exposure pathways to microplastics and nanoplastics through seafood, salt, drinking water, inhalation, and skin contact, examining how these particles cross biological barriers to reach organs and trigger oxidative stress, inflammation, and endocrine disruption with poorly understood long-term consequences.

Molecular mechanisms of microplastics toxicity