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Inflammatory Effects of Microplastics and Nanoplastics on Nasal Airway Epithelial Cells

International Forum of Allergy & Rhinology 2025 1 citation ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Maayan S. Kahan, Hoang C.B. Nguyen, Pallavi Madhusudanan, Margaret B. Mitchell, Di Huang, Benjamin S. Bleier, Mansoor M. Amiji, Alan D. Workman

Summary

Researchers found that polystyrene micro- and nanoplastics cause inflammatory cytokine responses in nasal epithelial cells even over short exposure periods. The study also observed ciliary blunting and transcriptional evidence of significant inflammation and stress responses, suggesting that the nasal airway is vulnerable to plastic particle exposure.

Polymers

PS MNPs cause inflammatory cytokine responses in nasal epithelial cells over even a short timeframe, in addition to ciliary blunting and transcriptional evidence of significant inflammation and stress response. This sinonasal model can help answer critical questions about the pathogenicity of plastic exposures.

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